Effects of Treatment with an Anti-IgE Drug on Patients with Chronic Sinusitis and a Positive Allergen Test
Study Summary
The purpose of this research study is to learn more about possible treatments for chronic sinusitis and nasal polyps. We will compare the effectiveness of a drug given by injection and currently used for the treatment of asthma with placebo (something that looks like the active medication but does not contain the active drug). The study drug is considered experimental in this study because it is not approved by the Food and Drug Administration for the treatment of chronic sinusitis or nasal polyps. This research is being done because currently, even with the surgical and medical treatments available, there are still many patients who suffer from this disease. Participation in this study will last approximately six months, with once or twice (depending on the dose of study drug required) monthly visits.
Participation Details
- Adults age 18 to 75 years.
- Must have chronic sinusitis (defined by symptoms for more than 12 weeks despite treatment).
- Positive sinus CT scan.
- Positive allergy test (skin or blood test).
- Must have a body weight less than 330 pounds.
- May not have significant heart, lung, kidney or liver disease.
Study Director: Robert Naclerio, MD
Department: Otolaryngology-Head and Neck Surgery
For more information, please contact:
Marcy deTineo, RN
5841 S. Maryland Ave., MC1035
Chicago, IL 60637
(773) 702-5889
mdetineo@surgery.bsd.uchicago.edu
IRB: #13916A
