Experimental Therapy for Patients with Acne

Study Summary

The University of Chicago and Dr. Tsoukas are conducting a study to evaluate the efficacy of two different light therapies used in combination with a topical drug to help people with acne vulgaris. Acne vulgaris (commonly known as acne) is a skin condition that affects 85 to 100 percent of the general population at some time during their lives, especially during adolescent years. The purpose of this study is to see whether applying a drug to the area of the skin affected by acne and using two different types of lights to act upon the drug will relieve the acne. Both of the lights used in combination with the drug are experimental meaning that they have not been approved by the Food and Drug Administration for the treatment of acne.

For the purposes of this study, you will undergo a procedure using both of the light therapies. First the topical drug will be applied to the affected area. Then, the study doctor will expose one side of your face or the area affected by acne with one type of light for a short time period. After that, the opposing side of the affected area will be exposed to the second type of light. After the procedure is completed, you will be asked to return for follow up at one, two, seven, and 30 days after the procedure. You will be given instructions on how to take care of your skin after the procedure. Depending on how well your skin responds to the procedure, you may also repeat it up to five times. Regardless of how many times you undergo the procedure, you will be asked to return to the clinic twice a month for 18 months following your last procedure.

There may be no benefit to you for participating in this study. The information learned about this experimental therapy and how it works may helpful to patients with acne in the future.

Participation Details

• Must be at least 18 years of age
• Must have tried and failed treatment with topical retinoids and topical and oral antibiotics
• Must be available for clinic visits for the duration of the study
• Must meet study medical criteria as evaluated by Dr. Tsoukas

Study Director: Dr. Maria Tsoukas
Department: Dermatology

For more information contact:
Irene Vergilis, MD
irene.vergilis@uchospitals.edu

IRB: #15929B