Research Study for Patients Receiving a Pacemaker

The University of Chicago and Dr. John F. Beshai are conducting a study for people who are scheduled to receive a pacemaker.

The purpose of this clinical research study is to compare the effectiveness of the CYLOS pacemaker programmed with Closed Loop Stimulation (CLS) to the CYLOS pacemaker programmed to other modes. CLS is a new concept of heart rate modulation in cardiac pacing. The objective of this study is to demonstrate that patients with sensor driven rates will achieve a more appropriate heart rate when performing Activities of Daily Living while programmed to a CLS pacing mode than patients programmed to standard modes.

The pacemakers used in this study are approved by the Food and Drug Administration (FDA). Participation in the study is expected to last 12 months.

There may be some medical benefit related to the use of pacemakers equipped with CLS or motion based rate response. These pacemakers may provide more appropriate heart rates during physical activity than other pacemakers, however this cannot be guaranteed.

Participation Details

Initial selection criteria include:

• Scheduled to receive a CYLOS pacemaker utilizing CLS
• Must be available for clinic visits for the duration of the study
• Must be at least 18 years of age
• Must meet study medical criteria as evaluated by Dr. Beshai

Study Director: Dr. John F. Beshai
Department: Cardiology

For more information contact:
Melody Altman
(773) 834-7157

IRB: #16225A