Do You Have Heart Failure?

The University of Chicago and Dr. Burke are conducting a study for people who are scheduled to receive a cardiac resynchronization therapy device (CRT-D) for their heart failure.

This study will compare the benefits of three different ways of optimizing your CRT-D device. Optimizing means that the study doctor will use timing features to program your device in an effort to improve the treatment you receive. The purpose of this research study is to determine how these different methods for determining the programming of your CRT-D device affect the heart. The measurements can be made in three different ways: 1) Using a standard preset setting in your CRT-D device, 2) Using measurements taken by your CRT-D device, 3) Using echocardiography (an ultrasound of the heart that shows moving pictures of the heartbeat). All of these methods are currently used as standard of care and are not considered experimental.

The CRT-D device is approved by the FDA (Food and Drug Administration) for the treatment of people with advanced heart failure and altered electrical conduction within the heart. You will be in this study for approximately six months and have five visits to the clinic.

You may or may not receive any medical benefit from participating in this study. However, medical science and future patients like you may benefit from your participation.

Participation Details

Initial selection criteria include:

• Must be at least 18 years of age
• Must not be pregnant
• Must be available for clinic visits for the duration of the study
• Must meet study medical criteria as evaluated by Dr. Burke

Study Director: Dr. Martin C. Burke
Department: Cardiology

For more information contact:
Melissa Byrn
(773) 834-7157

IRB: #16363B