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Bakhtiar Yamini, MD

Professor of Surgery

Director, Neurosurgical Oncology

Bakhtiar Yamini, MD, specializes in neuro-oncology, and he is an expert in minimally invasive neurosurgery for children and adults. This includes using sophisticated stereotactic techniques that allow for three-dimensional surgical planning. Dr. Yamini coordinates comprehensive surgical care for patients with central nervous system (CNS) tumors, including the use of minimally invasive procedures such as sterotactic biopsy, laser ablation, and the latest image-guided techniques for maximal resection of deep-seated tumors. He also has a strong interest in vascular neurosurgery and spine surgery.

In addition to his clinical work, Dr. Yamini conducts medical research. His National Institutes of Health (NIH) funded research focuses on examination of the mechanisms by which brain tumors resist treatment and the development of novel approaches to improve their management, including the use of biodegradeable nanoparticle vectors.

His current investigations explore cellular DNA damage response and the treatment of malignant brain tumors in children and adults. Additionally, Dr. Yamini has interests in intracranial and skull-base endoscopy research. As an active scholar, he has published articles and book chapters on current research topics, including brain/spinal tumors and craniosynostosis -- a congenital defect, which causes abnormalities in skull and brain development. Dr. Yamini's research has also received research funding from the American Cancer Society and the University of Chicago Comprehensive Cancer Center.

Practice Locations

Duchossois Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637

The University of Chicago Medicine Comer Children's Hospital
5721 S. Maryland Avenue
Chicago, IL 60637

Year Started Practice


Board Certification

Neurological Surgery

Medical School

University of Michigan Medical School

Internship and Residency

The University of Chicago Medicine


American Association of Cancer Research
American Association of Neurological Surgeons
American Medical Association
Chicago Surgical Society
Child Neurology Society
Congress of Neurological Surgeons
Society for Neurooncology

Languages Spoken



Office Phone

(773) 702-4452

Office Fax

(773) 702-3518

Office Postal Address

Bakhtiar Yamini, MD
The University of Chicago Medicine
5841 S. Maryland Avenue, MC 3026
Chicago, IL 60637

Physician Photo

Clinical Interests

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Learn More About Dr. Yamini

Gloria Fletcher says she felt peaceful and unafraid before undergoing surgery to remove a life-threatening meningioma in her brain. “Dr. Yamini eased my fears and calmed me down,” she said. Read Gloria’s story.

Within seconds of meeting Dr. Yamini, Susan Tyra and her husband were assured that they found the right expert to remove the meningioma that was pressing on her brain stem. Read Susan's story.

Pamela Hsieh was just 19 when a stroke paralyzed her left side. After treatment at the medical center, Hsieh has regained enough movement to hike mountains. Dr. Yamini is featured in a video and story about Hsieh's experience.

Dr. Yamini is part of a multispecialty team that provides care for both adults and children with congenital anomalies of the nervous system, including Syringomyelia, Hydrocephalus, Chiari Malformation, Spina Bifida, and more.

The Science Life blog featured Dr. Yamini in a post about the use of nanoparticles to deliver chemotherapy drugs to hard-to-reach brain tumors. Read more.

Selected Publications

View a partial list of Dr. Yamini's publications through the National Library of Medicine’s publication database.