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Charles Rubin, MD

Associate Professor of Pediatrics

An authority on all pediatric cancers, Dr. Charles Rubin has been overseeing the care of children for more than 25 years. He is a strong believer in educating patients and their families -- and in involving them in the decision process in a meaningful way.

Remembering Dr. Rubin

Dr. Rubin has worked to uncover the genetic basis for cancer through laboratory research aimed at identifying the chromosomal abnormalities that occur in childhood cancers. He is involved in clinical trials for childhood cancer treatments and has published numerous articles in top medical journals on leukemia, lymphoma, retinoblastoma and other diseases.

While he treats all childhood cancers, Dr. Rubin is especially interested in brain tumors and tumors occurring in children with genetic syndromes.

Dr. Rubin collaborates with physicians around the nation through the Children’s Oncology Group and the National Cancer Institute.

Practice Locations

The University of Chicago Medicine
Comer Children's Hospital
5721 S. Maryland Avenue
Chicago, IL 60637

University of Chicago Medicine Comer Children's at Edward
Medical Office Building II
120 Spalding Drive, Suite 200
Naperville, IL 60540

University of Chicago Medicine Comer Children's at Elmhurst
1200 S. York Street, Suite 3190
Elmhurst, IL 60126

University of Chicago Pediatric Specialists
8528 Broadway
Merrillville, IN 46410

University of Chicago Medicine Comprehensive Cancer Center
1850 Silver Cross Blvd.
New Lenox, IL 60451

Year Started Practice


Board Certifications

Pediatric Hematology/Oncology
Medical Genetics

Medical School

Tufts University School of Medicine

Internship and Residency

Children's Hospital, Philadelphia


University of Minnesota Medical Center, Minneapolis
The University of Chicago Medicine


American Academy of Pediatrics
American Society of Pediatric Hematology/Oncology
Society for Neuro-Oncology

Language Spoken



Office Phone

(773) 702-6808

Office Fax

(773) 702-9881

Office Postal Address

Charles Rubin, MD
The University of Chicago Medicine
5841 S. Maryland Avenue, MC 4060
Chicago, IL 60637

Physician Photo

Clinical Interests

Learn More About Dr. Rubin

William Dawes was diagnosed with a rare spinal cord tumor at the age of 7. Now, a decade later, the college freshman is pursuing his dreams as Dr. Rubin cheers him on. Read the story.

The astrocytoma in Daniel’s brain was inoperable, and growing in a particularly critical location. Dr. Rubin led an innovative, team-based treatment plan that successfully stopped the tumor from growing and threatening Daniel’s well-being. Read his story.

When Steve and Laura's daughter was diagnosed with acute lymphoblastic leukemia, they reached out to the University of Chicago Medicine and were immediately comforted by Dr. Rubin’s treatment philosophy.

Dr. Rubin serves as a Chapter Medical Advisor for Make-A-Wish Illinois. Learn more.

Selected Publications

View a partial list of Dr. Rubin's publications through the National Library of Medicine's PubMed online database.