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Deborah Loeff, MD

Assistant Professor of Surgery

Deborah Loeff, MD, is a specialist in pediatric general surgery. She has particular expertise in the treatment of children with complex congenital anomalies, such as tracheoesophageal fistula and esophageal atresia, abdominal wall defects; gastrointestinal conditions, including inflammatory bowel disease and gastroesophageal reflux; pediatric cancer; and traumatic injuries. Dr. Loeff is highly skilled in minimally invasive surgery used to treat many conditions in the chest and abdomen. Because this surgical technique involves tiny instruments and smaller incisions, patients experience less pain, minimal scarring and a faster recovery. It is frequently the best choice for children. Dr. Loeff feels that successful care of a child with a surgical condition requires engaging parents in all aspects of evaluation and management.

As a member of the Level 1 pediatric trauma team at the University of Chicago Medicine Comer Children’s Hospital, Dr. Loeff works with an interdisciplinary program dedicated to providing the optimal treatment for children who sustain injuries from trauma. In addition to providing medical care to these patients, Dr. Loeff works to identify strategies for prevention and advocates for improved systems of care.

Practice Locations

The University of Chicago Medicine
Comer Children’s Hospital
5721 S. Maryland Avenue
Chicago, IL 60637

Year Started Practice


Board Certifications

Pediatric Surgery
General Surgery

Medical School

Rush University Medical College

Internship and Residency

University of Utah Affiliated Hospitals, Salt Lake City


Hospital for Sick Children, Toronto, Canada


American College of Surgeons
American Pediatric Surgical Association
Association of Women Surgeons
Chicago Committee on Trauma
Chicago Medical Society
Chicago Surgical Society
Illinois State Medical Society
International Pediatric Endosurgical Group

Language Spoken



Office Phone

(773) 702-6175

Office Fax

(773) 702-1192

Office Postal Address

Deborah Loeff, MD
The University of Chicago Medicine
5841 S. Maryland Avenue, MC 4062
Chicago, IL 60637

Physician Photo

Clinical Interests

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Read More About Dr. Loeff

Dr. Loeff was one of dozens of specialists who cared for an infant born with a large neck tumor called a cervical teratoma. After the baby boy’s complex delivery, Dr. Loeff performed delicate surgery to remove the large tumor, preserving the healthy tissue and nerves nearby. Read John Carlos’ birth story.

Selected Publications

View a partial list of Dr. Loeff's publications through the National Library of Medicine's PubMed online database.