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Ernst Lengyel, MD, PhD

Arthur L. and Lee G. Herbst Professor of Obstetrics/Gynecology

Chairman, Department of Obstetrics/Gynecology

Ernst Lengyel, MD, PhD, is an expert in the diagnosis and treatment of gynecologic malignancies, specifically, ovarian, cervical and endometrial cancers. His primary clinical focus is on the treatment of ovarian cancer, including advanced surgical techniques designed to improve patient outcomes.

Dr. Lengyel performed the University of Chicago's first laparoscopic pelvic and para-aortic lymph node dissection for gynecologic cancer. He also performs radical vaginal trachelectomy (RVT) to preserve fertility in young patients who have cervical cancer.

Dr. Lengyel has been recognized by Chicago magazine as one of the city's "Top Doctors" for ovarian and cervical cancer care. He is also skilled in complex pelvic surgeries for benign gynecologic conditions, such as endometriosis and fistula repairs.

Dr. Lengyel's research laboratory in the Center for Integrative Science focuses on the investigation of new therapies for the treatment of ovarian cancer. His research is funded by the National Institutes of Health (NIH). In addition to clinical and research activities, Dr. Lengyel mentors residents and postdoctoral fellows in the Department of Obstetrics/Gynecology.

Practice Locations

Duchossois Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637

The University of Chicago Medicine
5841 S. Maryland Avenue
Chicago, IL 60637

Year Started Practice


Board Certifications

Obstetrics & Gynecology
Gynecologic Oncology


Gynecologic Oncology

Medical School

Ludwig-Maximilian University

Internship and Residency

University of Munich


University of California, San Francisco
Stanford University


American Association for Cancer Research
American Association for the Advancement of Science
German Association of Academic Teachers
Society of Gynecologic Oncology

Languages Spoken



Office Phone

(773) 702-6118

Office Fax

(773) 702-5411

Office Postal Address

Ernst Lengyel, MD, PhD
The University of Chicago Medicine
5841 S. Maryland Avenue, MC 2050
Chicago, IL 60637

Physician Photo

Clinical Interests

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Learn More About Dr. Lengyel

Learn more about optimized pregnancy and childbirth care at the Family Birth Center.

When cervical cancer threatened Jennifer Mason Zinga's dream of having three children, she wasn't ready to give up hope. After a radical vaginal trachelectomy (RVT), performed by Dr. Lengyel, Zinga is cancer-free and a mom of three.

Dr. Lengyel leads a team of researchers in the study of ovarian cancer and the investigation of new treatments.

After being treated by Dr. Lengyel for ovarian cancer, Allison Sharpe became an active advocate for awareness of the disease and a mentor to other patients. Read Allison's story

Selected Publications

View a partial list of Dr. Lengyel's publications through the National Library of Medicine's PubMed online database.