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Hue Luu, MD

Associate Professor of Orthopaedic Surgery

Associate Director, Molecular Oncology Lab

Hue H. Luu, MD, specializes in hip and knee replacements as well as the surgical care of bone and soft tissue tumors. He is an expert in both direct anterior approach and mini-posterior approach total hip replacements. Direct anterior approach total hip replacement is a more muscle sparing and less invasive technique that allows for a more rapid recovery. He also uses the state of the art Robotic-Arm Assisted technology for total hip, total knee and partial knee replacement surgeries. Robotic assistance allows for more precision and less soft tissue damage. He strives to give outstanding care to his patients to help restore their quality of life and function. Dr. Luu works with a multidisciplinary physician team to provide comprehensive care for patients with benign and malignant musculoskeletal tumors.

His research interests include: the fundamental mechanisms regulating bone biology and bone regeneration, osteolysis in total joint replacement patients, and advances in gene therapy to study applications of bone biology in fracture care. Dr. Luu also has an interest in studying genes that control cancer metastasis, for the purpose of identifying new diagnostic and therapeutic approaches for treating malignant cancers.

Practice Locations

The University of Chicago Medicine
5841 S. Maryland Avenue
Chicago, IL 60637

Duchossois Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637

University of Chicago Medicine Center for
Advanced Care at Orland Park
14290 S. La Grange Rd 
Orland Park, IL 60462

Year Started Practice


Board Certification

Orthopaedic Surgery

Medical School

The University of Chicago Pritzker School of Medicine

Internship, Residency and Fellowship

The University of Chicago Medicine


American Academy of Orthopaedic Surgeons
Metastasis Research Society
Orthopaedic Research Society

Language Spoken


Office Phone

(773) 834-3531 

Office Fax

(773) 702-4765

Office Postal Address

Hue Luu, MD
The University of Chicago Medicine
5841 S. Maryland Avenue, MC 3079
Chicago, IL 60637

Physician Photo

Clinical Interests

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Learn More About Dr. Luu

Dr. Luu performed robotic-arm assisted knee replacement surgery on both Michael and Karen Gamperl, enabling them to return to normal activities in just weeks.

Dr. Luu used computer-assisted navigation to perform limb-sparing surgery for a young man with osteosarcoma.

Selected Publications

View a partial list of Dr. Luu's publications through the National Library of Medicine's PubMed online database.