Issam A. Awad, MD
John Harper Seeley Professor of Surgery
Director, Neurovascular Surgery
Issam A. Awad, MD, has expertise in neurosurgery. He is skilled in the surgical management of neurovascular conditions affecting the brain and spinal cord, including cerebral aneurysms, cerebrovascular malformations, hemorrhagic stroke and skull base tumors.
Dr. Awad's research focuses on vascular biology, genetics, and comprehensive outcome analysis in neurovascular disease and stroke. His active projects include National Institutes of Health (NIH) funded investigations of molecular mechanisms involved in the formation and progression of cerebrovascular malformations. Additionally, he leads several clinical trials on minimally invasive techniques for surgical treatment of hemorrhagic stroke.
Dr. Awad’s research contributions have spanned more than two decades. His scientific innovations include the characterization of subcortical ischemic lesions in the aged, advances in the understanding of the natural history and biologic behavior of cerebral vascular malformations, and numerous technical advances in neurovascular and epilepsy surgery.
Recognized as a pioneering and productive scholar, Dr. Awad has educated scores of neurosurgeon trainees and holds prominent editorial responsibilities. He has authored leading textbooks and published more than 250 scholarly papers related to clinical innovations, surgical outcomes and research.
Additionally, Dr. Awad has been elected to some of the most distinguished professional societies and has held leadership positions in professional and learned societies in the United States and around the world. He has served as President of the Congress of Neurological Surgeons, Chairman of the Cerebrovascular Section of the American Association of Neurological Surgeons, Chairman of the Congress of Neurological Surgeons, and on the Executive Committee of the American Stroke Association and the Board of Governors of the American College of Surgeons. He is the Founding Chairman of the Scientific Advisory Board of Angioma Alliance.
The University of Chicago Medicine
Center for Advanced Medicine
University of Chicago Physicians at Matteson
Year Started Practice
Loma Linda University, CA
Loma Linda University Medical Center, CA
Cleveland Clinic, OH
The Royal Infirmary of Edinburgh, Scotland, UK
Alpha Omega Alpha Honor Medical Society
Office Postal Address
Issam A. Awad, MD
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More About Dr. Awad
Dr. Awad’s cerebral cavernous malformation (CCM) clinic attracts patients from around the world. Learn how he helped 4-year-old Zane Smith, whose family traveled from Cambridge, England to seek Dr. Awad’s expertise.
Ohio resident Sherry Kedra sought out Dr. Awad after a cerebral cavernous malformation (CCM) leaked into her brain. When a second CCM bled a year later, Kedra returned to Chicago for surgery. Read Sherry's story.
After suffering a massive stroke, a patient credits Dr. Awad's expert care for giving him a second chance at life. Read Jim's story.
Dr. Awad successfully detected and removed a cerebral cavernous malformation (CCM) that had been causing Steven Steinhilber to experience seizures. Read Steven's story.
In a four-hour procedure, Dr. Awad, who has performed more than 800 such surgeries in his 25-year career, treated multiple cerebral aneurysms in a single operation.
Read how Dr. Awad removed a large tumor, a large meningioma, from the base of a woman’s brain, restoring her vision.
By performing an experimental procedure, Dr. Awad saved the life of a man who had experienced an intracerebral hemorrhage, a type of stroke.
The aneurysm deep in Angela Quashie's brain posed a serious threat to her well-being. Dr. Awad was confident that surgery was her best option, and he was right. Read Angela's story.
A pill to prevent brain surgery? Dr. Awad and his colleagues are investigating a drug that may lower the risk for people with the familial form of CCM.
View a partial list of Dr. Awad's publications through the National Library of Medicine's PubMed online database.