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J. Michael Millis, MD

Professor of Surgery

Vice Chair, Global Surgery

Dr. Michael Millis is an expert in adult and pediatric transplant surgery. His clinical interests include liver transplantation and hepatobiliary surgery. He has performed more liver transplants than any other surgeon in the region. Dr. Millis has pioneered new techniques of operating on the liver, and his innovations have helped the University of Chicago perform more liver transplants than any other program in the region over the past 15 years.

Dr. Millis's research explores the application of cellular technology to patient care. For instance, he is investigating how hepatocyte transplantation, extracorporeal assist technology and stem cells can assist in the care of patients with liver disease or liver tumors. His research interests also include health and policy ethics. He is a consultant to the Chinese Ministry of Health to help them transform their transplant system, including the development of a donor system for volunteer citizen deceased donors.

Practice Location

Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637

Year Started Practice


Board Certifications

General Surgery
Critical Care

Medical School

University of Tennessee College of Medicine

Residency and Fellowship

University of California, Los Angeles


American College of Surgeons
American Society of Transplant Surgeons
American Society of Transplantation
International Pediatric Transplant Association
Society of University Surgeons

Language Spoken



Office Phone

(773) 702-6319

Office Fax

(773) 702-7511

Office Postal Address

J. Michael Millis, MD
The University of Chicago Medicine
5841 S. Maryland Avenue, MC 5027
Chicago, IL 60637

Physician Photo

Clinical Interests

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Learn More About Dr. Millis

Dr. Millis has been assisting the Chinese government in overhauling their organ donation approach. Read more about his instrumental involvement in developing a more ethical organ donation system in China.

Learn about baby Raquel Allen, who received a liver transplant from her mother's co-worker. Dr. Millis was part of the transplant team, and is featured in video interviews about Raquel's transplant.

Dr. Millis is featured in a story about a family who traveled more than 7,000 miles to Chicago to have a father-to-son living donor liver transplant. »Read the story

In May 1999, University of Chicago physicians performed the second triple transplant in the world in which three totally different organ systems were involved. Dr. Millis transplanted the liver and kidneys in the critical heart, liver and kidney transplant operation.

Dr. Millis performed a liver cell infusion on a 3-pound premature infant with liver failure. The baby is the youngest and smallest person to receive this innovative form of liver "transplant."

Read about Dr. Millis and the ELAD (extracorporeal liver assist device)--a machine designed to serve as a temporary liver support for patients with acute liver failure.

Physicians at the University of Chicago performed a heart-liver transplant--the 10th time this procedure had been performed in the United States. Dr. Millis was part of the team that transplanted the liver.

Selected Publications

View a partial list of Dr. Millis' publications through the National Library of Medicine's PubMed online database.