Request an Appointment:
Online or Call 1-888-824-0200

James LaBelle, MD, PhD

Assistant Professor of Pediatrics

James LaBelle, MD, PhD, provides care for children of all ages with cancer and blood diseases, including leukemia and lymphoma. In particular, Dr. LaBelle specializes in stem cell transplantation, replacing a patient's diseased bone marrow and immune system with healthy cells.

Dr. LaBelle's laboratory research focuses on understanding at a molecular level the reason why some pediatric cancers are resistant to therapy. He currently serves as the primary investigator on a study examining a critical network of proteins that regulate whether a malignant cell lives or dies. The normal signaling between these proteins often is disturbed in cancerous cells. Through this research, he hopes to identify novel cell death regulatory mechanisms in resistant hematopoietic malignancies and design effective strategies to overcome them. Dr. LaBelle's research is currently funded by the National Institutes of Health.

A dedicated mentor, Dr. LaBelle also received special recognition for teaching medical students, residents, and fellows about pediatric hematology, oncology, and hematopoietic stem cell transplantation.

Practice Locations

The University of Chicago Medicine
Comer Children's Hospital
5721 S. Maryland Avenue
Chicago, IL 60637

Duchossois Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637

Year Started Practice


Board Certification


Medical School

Medical College of Wisconsin

Internship and Residency

Boston Combined Program, Children's Hospital Boston/Boston Medical Center


Children's Hospital Boston, Harvard Medical School
Dana-Farber Cancer Institute, Harvard Medical School

Additional Graduate Degrees

PhD, Medical College of Wisconsin, Milwaukee (Tumor Immunology; Microbiology and Molecular Genetics)


American Society for Blood and Marrow Transplantation
American Society of Hematology
American Association for Cancer Research

Language Spoken



Office Phone

(773) 702-6812

Office Fax

(773) 834-1329

Office Postal Address

James LaBelle, MD, PhD
The University of Chicago Medicine
5841 S. Maryland Avenue, MC 4060
Chicago, IL 60637

Physician Photo

Clinical Interests

Request an appointment online
or call UCM Connect at

Selected Publications

View a partial list of Dr. LaBelle's publications through the National Library of Medicine's PubMed online database.