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James K. Liao, MD

Harold Hines, Jr. Professor of Medicine

Chief, Section of Cardiology

James K. Liao, MD, is an expert in the diagnosis and treatment of cardiac diseases, including artherosclerosis (a build up of fatty deposits in artery walls), peripheral vascular disease (hardening/narrowing of the arteries), dyslipidemia (high blood cholesterol), and cerebrovascular disease. He specializes in non-invasive cardiology, using genetic and novel clinical markers and advanced imaging techniques to diagnose diseases of the heart and vascular system.

An active researcher, Dr. Liao's work examines the role of lipid-lowering medications in ischemic stroke, coronary artery disease, and heart failure. In particular, he focuses on identifying novel signaling pathways that control vascular function in both normal and diseased states. He has served as the primary investigator in numerous basic and clinical studies, working to translate his findings from the laboratory to patient care. His research has been funded by the National Institutes of Health (NIH) and the American Heart Association (AHA).

Dr. Liao has made significant contributions to medical literature, publishing more than 125 original articles in scientific journals, including Nature, Science, Nature Medicine, Journal of Clinical Investigation, and Circulation. He is an Established Investigator of the American Heart Association and has served on editorial boards of prominent journals. He is recognized as an elected member of the American Society for Clinical Investigation (ASCI) and the Association of American Physicians (AAP).

As a mentor, Dr. Liao has trained more than 60 research fellows, many of whom have won or were finalists for the prestigious American Heart Association and the American College of Cardiology Young Investigator Awards. Additionally, he is frequently invited to give lectures on the management of dyslipidemia, vascular disease and ischemic stroke at national and international conferences.

Dr. Liao is consistently listed among the Top Physicians by "Who's Who in American Doctors."

Practice Locations

The University of Chicago Medicine
5841 S. Maryland Avenue
Chicago, IL 60637

Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637

Year Started Practice


Board Certifications

Internal Medicine
Cardiovascular Diseases

Medical School

University of California San Francisco

Internship and Residency

Brigham and Women's Hospital, Harvard Medical School, Boston (internal medicine)


Harvard Medical School, Boston (research fellowship)
Massachusetts General Hospital, Boston (cardiology)


American College of Cardiology
American College of Physicians
American Federation for Medical Research
American Heart Association
American Society for Clinical Investigation
Association of American Physicians
Chinese American Medical Society

Languages Spoken



Office Phone

(773) 702-8950

Office Fax

(773) 702-1385

Office Postal Address

James K. Liao, MD
The University of Chicago Medicine
5841 S. Maryland Avenue, MC 6080
Chicago, IL 60637

Physician Photo

Clinical Interests

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Selected Publications

View a partial list of Dr. Liao's publications through the National Library of Medicine's PubMed online database.