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Kristi Tough DeSapri, MD

Clinical Assistant Professor of Obstetrics/Gynecology

Kristi Tough DeSapri, MD, is a board certified internist and completed a specialized fellowship in women’s health. She is dedicated to empowering women to be advocates for their health. Dr. Tough DeSapri an expert in managing care for a wide range of conditions that impact women and specializes in the following areas:

  • Menopause and perimenopause evaluation and treatment
  • Osteoporosis treatment
  • Contraceptive consultation

In additional to her clinical work, Dr. Tough DeSapri is an avid researcher and lectures nationally. She has investigated many key issues related to women's health, including osteoporosis, contraception and the development of the prophylactic breast cancer vaccine. Her work has been published in multiple peer-reviewed medical journals.

Practice Locations

University of Chicago Medicine Women's Care at Streeterville
680 North Lake Shore Drive
Suite 117
Chicago, IL 60611

University of Chicago Medical Center
5841 S. Maryland Avenue
Chicago, IL 60637

Year Started Practice


Board Certification

Internal Medicine

Medical School

University of Texas School of Medicine


New York University Medical Center


Lenox Hill Hospital


Cleveland Clinic


American College of Physicians
North American Menopause Society
International Society for Clinical Densitometry
American Society for Bone and Mineral Research

Language Spoken



Office Phone

(312) 654-1166

Office Fax

(312) 654-5288

Physician Photo

Clinical Interests

  • Abnormal periods
  • Abnormal uterine bleeding
  • Contraception
  • Female urinary incontinence
  • Menopause
  • Osteopenia
  • Osteoporosis
  • Perimenopause
  • Preventive medicine
  • Sexual dysfunction therapy
  • Reproductive issues
  • Midlife women’s health

Request an appointment

(312) 654-1166