Request an Appointment:
Online or Call 1-888-824-0200

Louis Philipson, MD, PhD

Professor of Medicine

Director, Kovler Diabetes Center

Louis Philipson, MD, PhD, is an endocrinologist and a leading world authority on diabetes mellitus. His clinical interests include type 1 diabetes, complicated type 2 diabetes, monogenic diabetes and hypoglycemia.

Recognized for unmatched expertise in the treatment of diabetes that is difficult to manage, Dr. Philipson's multisciplinary team frequently accepts referrals and provides consultations. Under his leadership, Kovler Diabetes Center has been recognized as a one of only seven National Institutes of Health (NIH) Diabetes Research and Training Centers in the U.S.

For more than 25 years, Dr. Philipson has tirelessly explored the biophysical, molecular and genetic aspects of insulin secretion, and the genetics of diabetes. He and his colleagues discovered rare insulin gene mutations that produce beta cell ER stress and, in turn, cause neonatal diabetes.

In addition, Dr. Philipson and his colleagues are among the nation's leading experts on monogenic diabetes, following more than 100 patients diagnosed with neonatal diabetes and many others with maturity onset diabetes of the young (MODY) type diabetes. He also serves as co-director of the Human Islet Transplantation project at the University of Chicago.

Dr. Philipson has served as principal investigator on numerous research projects. His work is widely published in biomedical journals, including the Proceedings of the National Academy of Sciences, Science, Nature, Diabetes, American Journal of Physiology and the Journal of Biological Chemistry.

As president of the Chicago/Northern Illinois board of the American Diabetes Association and a member of its National Board, he has been invited to speak and present at scientific research conferences and symposia worldwide. In addition, Dr. Philipson is the recipient of numerous awards including ADA Research Awards and the National Disease Research Interchange (NDRI) Outstanding Scientist Award. He was also named the 2011 recipient of the Samuel Eichold II Memorial Award for Contributions in Diabetes by the American College of Physicians.

Practice Locations

The University of Chicago Medicine
5841 S. Maryland Avenue
Chicago, IL 60637

Duchossois Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637

Year Started Practice


Board Certifications

Endocrine, Diabetes & Metabolism
Internal Medicine

Medical School

The University of Chicago Pritzker School of Medicine

Internship, Residency and Fellowship

The University of Chicago Medicine

Additional Graduate Degree

PhD, University of Chicago (Biochemistry)


American College of Physicians
American Diabetes Association
Juvenile Diabetes Foundation International
European Society for Study of Diabetes

Language Spoken



Office Phone

(773) 702-6138

Office Fax

(773) 702-2771

Office Postal Address

Louis Philipson, MD, PhD
The University of Chicago Medicine
5841 S. Maryland Avenue, MC 1027
Chicago, IL 60637

Physician Photo

Clinical Interests

Request an appointment online
or call UCM Connect at

Physicians, contact the
Referring Physician Access Line
at 1-877-DOM-2730

Learn More About Dr. Philipson

Learn more about Dr. Philipson and his colleagues in the University of Chicago Kovler Diabetes Center.

Dr. Philipson is featured in "Journey to a Miracle: Freedom from Insulin," an independent documentary that focuses on the discovery of a groundbreaking discovery for monogenic diabetes.

Through his innovative research, Dr. Philipson uncovered a rare form of diabetes caused by a genetic mutation and developed a successful treatment.

Lilly Jaffe was diagnosed with a rare type of diabetes when she was just one month old. Dr. Philipson helped her to produce insulin, making Lilly the fourth such case to be treated in the United States. Read her story.

What Joey Knoop thought was just a cold turned out to be type 1 diabetes. After struggling with her blood sugar levels for year, Knoop was referred to Dr. Philipson and underwent an islet cell transplant to produce her own insulin. Read Joey’s story.

The University of Chicago Medicine's Science Life blog features Dr. Philipson in a video about the real human effects of a scientific breakthrough in diabetes care.

Dr. Philipson, along with members of congress, was part of the team that declared an inaugural Diabetes Awareness Day in Illinois. Read the story.

Learn how Dr. Philipson's high-profile study boosted efforts to reverse type-1 diabetes.

Selected Publications

View a partial list of Dr. Philipson's publications through the National Library of Medicine's PubMed online database.