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Marcus R. Clark, MD

Professor of Medicine and Pathology

Chief, Section of Rheumatology

Co-Director, Knapp Center for Lupus and Immunology Research

Dr. Marcus Clark is a nationally known expert in arthritis and autoimmune disease, including rheumatoid and psoriatic arthritis, lupus, scleroderma and osteoarthritis.

Funded by the National Institutes of Health, Dr. Clark’s research examines the key cellular components of the immune process with the goal of understanding the mechanisms and changing the course of autoimmune disease. He is also exploring the role that immune cells play in contributing to the kidney damage sometimes seen in lupus patients.

Dr. Clark is the author of more than 70 peer-reviewed articles in prestigious scientific journals including Science, Nature Immunology, Proceedings of the National Academy of Sciences and the Public Library of Science’s (PLoS) Biology and Immunity.

Practice Locations

The University of Chicago Medicine
5841 S. Maryland Avenue
Chicago, IL 60637

Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637

Year Started Practice


Board Certifications

Internal Medicine

Medical School

University of California

Internship and Residency

University of Michigan, Ann Arbor


University of California, San Francisco


American Association of Immunologists
American College of Rheumatology
American Society for Clinical Investigation
Henry Kunkel Society

Language Spoken



Office Phone

(773) 702-6119

Office Fax

(773) 702-8702

Office Postal Address

Marcus R. Clark, MD
The University of Chicago Medicine
5841 S. Maryland Avenue, MC0930
Chicago, IL 60637

Physician Photo

Clinical Interests

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Selected Publications

View a partial list of Dr. Clark’s publications through the National Library of Medicine's PubMed online database.