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Matthew Sorrentino, MD

Professor of Medicine

Associate Director, Bucksbaum Institute for Clinical Excellence

Dr. Matthew Sorrentino is a non-invasive preventive cardiologist with expertise and research interests in treating hyperlipidemia (high cholesterol), hypertension and coronary artery disease. He is a general cardiologist, and he treats patients with all types of heart disease and risk factors for heart disease.

A popular speaker, Dr. Sorrentino has been invited to give lectures and run education programs at more than 500 local, national and international meetings and events. He has written numerous publications on preventive cardiology, including a recent book, “Hyperlipidemia in Primary Care”.

In 1999, Dr. Sorrentino was designated a specialist in hypertension by the American Society of Hypertension. In addition, he was honored by Chicago magazine as one of the top cardiologists in the Chicago area in 2000, 2008, 2010 and 2011. He was named as one of the Best Doctors in America in 2007. In 2011, he was appointed the Associate Director of the Bucksbaum Institute for Clinical Excellence.

Practice Locations

Duchossois Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637

150 E. Huron Street
Suite 900
Chicago, IL 60611

Year Started Practice


Board Certifications

Internal Medicine

Medical School

The University of Chicago Pritzker School of Medicine

Internship and Residency

The University of Chicago Medicine


American College of Cardiology--Fellow
American Heart Association
American Society of Hypertension--Fellow

Language Spoken



Office Phone

(773) 702-6924

Office Fax

(773) 702-8875

Office Postal Address

Matthew Sorrentino, MD
The University of Chicago Medicine
5841 S. Maryland Avenue, MC 6080
Chicago, IL 60637

Physician Photo

Clinical Interests

Request an Appointment

Center for Advanced Medicine
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150 E. Huron Street
Request an appointment online
or call (773) 834-4150

Physicians, contact the
Referring Physician Access Line
at 1-877-DOM-2730

Learn More About Dr. Sorrentino

Dr. Sorrentino explains to ScienceLife how certain genetic data can play a role in determining the most effective cardiovascular medications.

Dr. Sorrentino is the associate director of the Bucksbaum Institute for Clinical Excellence, a unique initiative that aims to enhance the skills of physicians as advisers, counselors and navigators to help patients make informed decisions when facing complex treatment choices.

The University of Chicago Medicine's Science Life blog featured Dr. Sorrentino in a brief video discussing heart attack risk factors, and how doctors can use risk assessments to guide interventions that offer fast, powerful risk reduction.

Selected Publications

View a partial list of Dr. Sorrentino's publications through the National Library of Medicine's PubMed online database.