Michael J. Thirman, MD

Associate Professor of Medicine

Dr. Michael Thirman specializes in the medical management of adults with leukemia, lymphoma, myelodysplastic syndromes, and myeloproliferative disorders. His laboratory focuses on the role of MLL and ELL in the development of leukemia.

In MLL-ELL associated leukemia, the normal protein-protein interactions of MLL and ELL are disrupted. Dr. Thirman's lab has recently identified two novel proteins, named EAF1 and EAF2, which interact specifically with ELL. Using a bone marrow immortalization assay and a mouse leukemia model, they found that the interaction of EAF1 with ELL is essential to MLL-ELL induced leukemia. Using model systems, Dr. Thirman’s laboratory plans to analyze the pathways that mediate leukemogenesis and then translate this knowledge into the development of novel treatment strategies.

Practice Locations

Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637

University of Chicago Medical Center
5841 S. Maryland Avenue
Chicago, IL 60637

Year Started Practice

1989

Board Certifications

Internal Medicine
Medical Oncology

Medical School

University of Michigan, Ann Arbor

Residency

University of Minnesota

Fellowship

University of Chicago Medical Center

Membership

American Society of Hematology

Language Spoken

English

Email

mthirman@medicine.bsd.uchicago.edu

Office Phone

(773) 702-6149

Office Fax

(773) 702-0963

Office Postal Address

Michael J. Thirman, MD
University of Chicago Medical Center
5841 S. Maryland Avenue, MC 2115
Chicago, IL 60637

Clinical Interests

• Hematologic malignancies
• Leukemia
• Lymphoma
• Myeloproliferative disorders
• Myelodysplastic syndromes

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1-888-UCH-0200

Physicians, contact the
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at 1-877-DOM-2730

Selected Publications

View a partial list of Dr. Thirman's publications through the National Library of Medicine's PubMed online database.