Request an Appointment:
Online or Call 1-888-824-0200

Michael J. Thirman, MD

Associate Professor of Medicine

Dr. Michael Thirman specializes in the medical management of adults with leukemia, lymphoma, myelodysplastic syndromes, and myeloproliferative disorders. His laboratory focuses on the role of MLL and ELL in the development of leukemia.

In MLL-ELL associated leukemia, the normal protein-protein interactions of MLL and ELL are disrupted. Dr. Thirman's lab has recently identified two novel proteins, named EAF1 and EAF2, which interact specifically with ELL. Using a bone marrow immortalization assay and a mouse leukemia model, they found that the interaction of EAF1 with ELL is essential to MLL-ELL induced leukemia. Using model systems, Dr. Thirman’s laboratory plans to analyze the pathways that mediate leukemogenesis and then translate this knowledge into the development of novel treatment strategies.

Practice Locations

Duchossois Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637

The University of Chicago Medicine
5841 S. Maryland Avenue
Chicago, IL 60637

Year Started Practice


Board Certifications

Internal Medicine
Medical Oncology

Medical School

University of Michigan Medical School


University of Minnesota


The University of Chicago Medicine


American Society of Hematology

Language Spoken


Office Phone

(773) 702-6149

Office Fax

(773) 702-0963

Office Postal Address

Michael J. Thirman, MD
The University of Chicago Medicine
5841 S. Maryland Avenue, MC 2115
Chicago, IL 60637

Physician Photo

Clinical Interests

Request an appointment online
or call UCM Connect at

Physicians, contact the cancer intake line at (773) 702-8222.

Selected Publications

View a partial list of Dr. Thirman's publications through the National Library of Medicine's PubMed online database.