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Peleg Horowitz, MD, PhD

Assistant Professor of Surgery

Peleg M. Horowitz, MD, PhD, is a neurosurgeon with expertise in brain tumors and skull base tumors. He provides multidisciplinary care as a member of the neuro-oncology and skull base tumor teams. Dr. Horowitz uses endoscopic and open surgical approaches to the skull base, including advanced stereotactic and 3-D surgical planning for operative treatment and radiosurgery of both benign and malignant brain tumors. In addition to his specialization in neurosurgical oncology, he also provides general neurosurgical care, treating patients with a wide range of conditions, including hydrocephalus, head trauma, and spine pathology in adults and children.

Dr. Horowitz conducts clinical and basic science research, with emphasis on the genetics of brain and skull base tumors. His scholarly work has focused on the pathogenesis and management of nervous system tumors and on the genetic characterization of tumors, controversies in current management and decision-making, surgical technique and complication avoidance. His research on tumor genetics has been published in Nature Genetics and Proceedings of the National Academy of Sciences, and identified several novel genes that drive the formation of meningiomas and pediatric gliomas. His research has been funded by the Brain Science Foundation and the Department of Defense Neurofibromatosis Research Program.

Practice Locations

Duchossois Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637

University of Chicago Medicine Comer Children's Hospital
5721 S. Maryland Avenue
Chicago, IL 60637

Year Started Practice


Medical School

Northwestern University (Feinberg School of Medicine), Evanston, IL

Internship and Residency

Brigham and Women's Hospital/Children's Hospital Boston (Harvard Medical School)


University of Texas MD Anderson Cancer Center (neurosurgical oncology and skull base neurosurgery)

Additional Graduate Degree

PhD, Northwestern University Graduate School, Institute for Neurosciences, Evanston, IL


American Association of Neurological Surgeons
Congress of Neurological Surgeons
Society of Neurological Surgeons

Languages Spoken



Office Phone

(773) 702-2123

Office Fax

(773) 702-3518

Office Postal Address

Peleg Horowitz, MD, PhD
University of Chicago Medical Center
5841 S. Maryland Avenue, MC 3026
Chicago, IL 60637

Clinical Interests

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Selected Publications

View a partial list of Dr. Horowitz's publications through the National Library of Medicine's PubMed online database.