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Peter Warnke, MD

Professor of Surgery

Director, Stereotactic and Functional Neurosurgery

Internationally renowned neurosurgeon Peter Warnke, MD, has performed more than 6,000 stereotactic surgeries and more than 3,000 brain tumor surgeries. Dr. Warnke provides neurosurgical care for the treatment of:

He routinely performs neurosurgical procedures with proven expertise, including:

Dr.Warnke is fellowship-trained in brain tumor surgery (neurooncology), movement and epilepsy surgery, and pediatric surgery. He has treated one of the largest series of low grade gliomas in adults and children (more than1,000) and intrinsic other brain tumors.

Dr. Warnke directs the MRI-Guided Laser Ablation Program for epilepsy and tumors, and is actively researching biological treatments for brain tumors (Lancet Oncology 2013).

In addition, Dr.Warnke has a large deep brain stimulation practice for Parkinson’s, essential tremor and dystonia, and was the first neurosurgeon in Chicago to use directional deep brain stimulation.

Dr. Warnke has a large epilepsy surgery practice and performs open resections, laser ablations and neurostimulation for epilepsy. He directs the SLATE trial in epilepsy surgery, investigating laser ablation as a new minimally invasive alternative to open surgery.

He has special expertise in stereotactic radiosurgery, including interstitial radiosurgery and stereotactically guided endoscopy. Dr. Warnke was one of the first neurosurgeons to use interstitial stereotactic radiosurgery for the treatment of gelastic epilepsy and hypothalamic hamartomas. He also provides care for patients with pain syndromes, including trigeminal neuralgia and neuropathic pain.

He is also researching the development of biological and minimally invasive treatments for epilepsy, movement disorders and brain tumors. Dr. Warnke is the associate editor of the Journal of Neurology, Neurosurgery and Psychiatry, which has the highest impact factor among neurosurgical journals. He also sits on the steering committees of several clinical trials, and has received ongoing extramural research funding for 20 years.

Practice Location

Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637

Year Started Practice


Board Certification

Neurological Surgery

Medical School and Internship

University of Freiburg, Germany


University Hospital Homburg, Germany


Northwestern University, Chicago
University of Chicago Medicine Comer Children's Hospital (pediatric neurosurgery)


American Association of Neurological Surgeons
American Epilepsy Society
Congress of Neurological Surgeons
European Society for Stereotactic and Functional Neurosurgery
International Stereotactic Radiosurgery Society
World Society for Stereotactic and Functional Neurosurgery

Languages Spoken



Office Phone

(773) 702-5595

Office Fax

(773) 702-3518

Office Postal Address

Peter Warnke, MD
The University of Chicago Medicine
5841 S. Maryland Avenue, MC 3026
Chicago, IL 60637

Physician Photo

Clinical Interests

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Read More About Dr. Warnke

Read Dr. Warnke’s Neurosurgery commentary on the surgical treatment of cystic craniopharyngiomas.

After meeting Dr. Warnke, Joseph Balogun was confident that he had selected the best neurosurgeon to remove the epidermoid tumor growing on his brain stem.

Dr. Warnke and his colleagues are among the first in the U.S. to successfully use new directional DBS technology.

For the first time in more than 40 years, Michael Segreto began to experience troubling seizure activity. After undergoing stereoelectroencephalography (SEEG) and laser ablation surgery, performed by Dr. Warnke, Michael is seizure-free once again.

At age 70, Cheng Xiu Xu's Parkinson's disease symptoms and medication side effects left her unable to perform familiar activities, including playing her favorite sport: ping-pong. Just two days after Dr. Warnke placed a DBS implant, Xu was able to play ping-pong again. Read her story.

Dr. Warnke worked with a multidisciplinary team of specialists to diagnose and treat Leo Galati's primary central nervous system lymphoma (PCNSL), a rare tumor that occurs when cancerous lymphocytes are found in the brain, spinal cord or cerebrospinal fluid. Read Leo's story.

Patrick O'Brien has essential tremor. After hearing Dr. Warnke speak at an event, he came the University of Chicago Medicine for DBS. Now he's living without tremors. Read Patrick's story.

Using functional MRI, Dr. Warnke was able to skillfully pinpoint critical anatomy surrounding a meningioma in Vaughn Atkins’ brain. With Dr. Warnke’s surgical precision, Vaughn avoided loss of motor function and even regained the movement he lost as a result of the pressure the tumor placed on his brain. Read Vaughn's story.

Dr. Warnke precisely targeted a quiet grouping of neurons and implanted an electrode in Betty Bertram's brain to control the essential tremor afflicting the left side of her body. Read Betty's story.

Selected Publications

View a partial list of Dr. Warnke's publications through the National Library of Medicine’s publication database.