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Raymond P. Roos, MD

Marjorie and Robert E. Straus Professor of Neurology

The Committees on Immunology, Neurobiology, and Microbiology

Director, Amyotrophic Lateral Sclerosis (ALS)/Motor Neuron Disease Clinic

Raymond P. Roos, MD, is an established expert on neurodegenerative diseases (such as amyotrophic lateral sclerosis (ALS) and prion diseases (e.g., Creutzfeldt-Jakob disease), multiple sclerosis (MS), inflammatory central nervous system diseases, and neuropathy. He directs the ALS/Motor Neuron Disease clinic.

A basic goal of Dr. Roos' research studies is to use molecular techniques to better understand the pathogenesis of MS and ALS. For instance, in one investigation, he and his colleagues sought to identify genes and gene products critical to the death and survival of motor neurons--especially as related to neurodegenerative diseases such as ALS. The lab uses viruses and transgenic mouse models in order to clarify the mechanisms by which mutant genes kill the target neurons.

Practice Location

Duchossois Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637

Year Started Practice


Board Certification


Medical School

SUNY Downstate Medical Center College of Medicine


SUNY, Downstate Medical Center, New York


Johns Hopkins Hospital, Baltimore, MD


American Academy of Neurology
American Neurological Association
American Society for Virology
Society for Neuroscience

Language Spoken



Office Phone

(773) 702-5659

Office Fax

(773) 834-9089

Office Postal Address

Raymond P. Roos, MD
The University of Chicago Medicine
5841 S. Maryland Avenue, MC 2030
Chicago, IL 60637

Physician Photo

Clinical Interests

  • Neurology
  • Amyotrophic lateral sclerosis (ALS)
  • Neurodegenerative diseases
  • Multiple sclerosis (MS)
  • CNS inflammatory diseases
  • Neuropathy

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Read More About Dr. Roos

Read about Dr. Roos' patient who was diagnosed with ALS in 2004 and now advocates for research in hopes of finding a cure for this neurodegnerative disease.

Learn why Dr. Roos is optimistic about the future of neurodegenerative disease and ALS research. “I think the field is on fire now,” he said.

Selected Publications

View a partial list of Dr. Roos's publications through the National Library of Medicine's publication database.