Roy E. Weiss, MD, PhD

Rabbi Esformes Professor of Medicine and Pediatrics

Chief, Section of Adult and Pediatric Endocrinology, Diabetes and Metabolism

Deputy Provost for Research

Executive Vice Chair of Medicine

Dr. Roy Weiss is an expert in diseases of the thyroid and pituitary disorders--such as Cushing’s disease. Dr. Weiss has described several genetic diseases of the thyroid along with Dr. Samuel Refetoff. Together, they have one of the largest referral centers for genetic thyroid disease in the world. He also has one of the largest programs in the Midwest in the diagnosis and treatment of Cushing’s disease.

His research centers on the mechanisms of thyroid hormone action at the molecular, physiological, and psychological levels. Dr. Weiss has examined the molecular basis for the syndrome of resistance to thyroid hormone (RTH). He also has several clinical studies evaluating treatment of thyroid disease. Dr. Weiss’ research is supported by funds from the National Institutes of Health (NIH).

In addition to teaching medical student courses in physiology and pathology, Dr. Weiss has been an invited speaker at national and international conferences. Dr. Weiss recently published a book, “Genetic Diagnosis of Endocrine Disorders” with Samuel Refetoff and he serves on the editorial board of Endocrinology. He has published more than 150 peer-reviewed articles on thyroid disease research and endocrinology.

Practice Locations

Duchossois Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637

The University of Chicago Medicine
5841 S. Maryland Avenue
Chicago, IL 60637

Year Started Practice


Board Certifications

Internal Medicine

Medical School

Tel Aviv University

Internship, Residency and Fellowship

The University of Chicago Medicine


American College of Physicians
American Medical Association
American Physiological Society
American Thyroid Society
Central Society for Research
The Endocrine Society

Languages Spoken



Office Phone

(773) 702-6138

Office Fax

(773) 834-3966

Office Postal Address

Roy E. Weiss, MD, PhD
The University of Chicago Medicine
5841 S. Maryland Avenue, MC 3090
Chicago, IL 60637

Physician Photo

Clinical Interests

  • Endocrinology
  • Endocrine cancers
  • Thyroid hormone resistance
  • Thyroid cancer
  • Thyroid diseases
  • Graves' disease
  • Cushing's disease
  • Pituitary disorders
  • Adrenal diseases

Request an appointment online
or call UCM Connect at

Physicians, contact the
Referring Physician Access Line
at 1-877-DOM-2730

Selected Publications

View a partial list of Dr. Weiss' publications through the National Library of Medicine's PubMed online database.