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Samuel L. Volchenboum, MD, PhD, MS

Associate Professor of Pediatrics

Associate Chief Research Informatics Officer

Director, Center for Research Informatics

Associate Director, Institute for Translational Medicine

Samuel L. Volchenboum, MD, PhD, MS, is an expert in pediatric cancers and blood disorders. He has a special interest in treating children with neuroblastoma, a tumor of the sympathetic nervous system.

In addition to caring for patients, Dr. Volchenboum studies ways to harness computers to enable research and foster innovation using large data sets. He directs the development of the International Neuroblastoma Risk Group Database project, which connects international patient data with external information such as genomic data and tissue availability. The Center he runs provides computational support for the Biological Sciences Division at the University of Chicago, including high-performance computing, applications development, bioinformatics, and access to the clinical research data warehouse. 

Practice Locations

Duchossois Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637

The University of Chicago Medicine Comer Children's Hospital
5721 S. Maryland Avenue
Chicago, IL 60637

Year Started Practice


Board Certifications

Pediatric Hematology/Oncology

Medical School

Mayo Medical School


Cincinnati Children's Hospital Medical Center


Children's Hospital, Boston (Harvard Medical School)
Dana-Farber Cancer Institute, Boston

Master's Degree

Massachusetts Institute of Technology, Boston
(Biomedical Informatics)


American Medical Informatics Association
American Society of Clinical Oncology
American Society of Pediatric Hematology/Oncology
Children's Oncology Group
The International Society for Computational Biology

Language Spoken



Office Phone

(773) 702-4303

Office Fax

(773) 834-1329

Office Postal Address

Samuel L. Volchenboum, MD, PhD, MS
The University of Chicago Medicine
5841 S. Maryland Avenue, MC 4060
Chicago, IL 60637

Physician Photo

Clinical Interests

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Learn More About Dr. Volchenboum

Dr. Volchenboum and other UChicago Medicine experts are collaborating with Google to use machine learning for better health care.

Read "Social Networks May One Day Diagnose Disease -- But at a Cost," an article Dr. Volchenboum wrote for Wired magazine.

The Washington Post featured Dr. Volchenboum in an article about how big data and predictive algorithms could potentially make hospitals safer for patients.

Learn how Dr. Volchenboum is using applied informatics techniques to better define cancer diagnoses, which in turn will allow physicians to create more tailored treatment plans.

Read Dr. Volchenboum's account of his experience caring for one young girl with high-risk neuroblastoma, and the role experimental treatments played in saving the girl's life.

Read about Dr. Volchenboum's neuroblastoma research and see photos from the St. Baldrick's event when he had his head shaved for science.

Selected Publications

View a partial list of Dr. Volchenboum's publications through the National Library of Medicine's PubMed online database.