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Sandeep Nathan, MD, MS

Associate Professor of Medicine

Director, Interventional Cardiology Fellowship Program

Director, Coronary Care Unit

Co-Director, Cardiac Catheterization Laboratory

Dr. Sandeep Nathan is a highly skilled cardiologist who specializes in interventional cardiovascular procedures. Dr. Nathan performs a wide range of coronary and peripheral vascular procedures for the diagnosis and treatment of cardiovascular disease, including balloon angioplasty, stenting, atherectomy, thrombectomy, cryoplasty and intravascular ultrasound imaging.

He is one of few interventional cardiologists who routinely perform transradial angiography and intervention, a less invasive alternative to traditional approaches. Transradial angiography uses an artery in the wrist, instead of the leg, as the entryway for diagnostic imaging and therapeutic procedures, such as angioplasty and stenting. This technique offers fewer risks and greater advantages, including increased patient comfort and immediate mobility following the procedure. Additionally, Dr. Nathan is a general cardiologist who treats patients with coronary artery disease (CAD), peripheral arterial disease (PAD) and risk factors for heart disease.

His research interests include platelet biology, interventional device therapies, intravascular imaging, and the use of antiplatelet and antithrombotic therapies (blood thinners) in the management of acute coronary syndromes and heart attacks. Dr. Nathan holds a master's degree in clinical research. He currently serves as a principal investigator or co-investigator on several clinical trials evaluating: new antiplatelet therapies in patients with acute coronary syndromes; novel stents for the treatment of coronary artery disease; and clinical outcomes in patients who have had percutaneous coronary interventions (angioplasty/stent) and heart attacks.

Practice Location

Duchossois Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637

Year Started Practice


Board Certifications

Internal Medicine
Cardiovascular Disease
Interventional Cardiology

Medical School

Boston University School of Medicine


University of Pittsburgh Medical Center


Rush University Medical Center, Chicago


American College of Cardiology
Society for Cardiovascular Angiography and Intervention

Languages Spoken



Office Phone

(773) 702-2697

Office Fax

(773) 702-0241

Office Postal Address

Sandeep Nathan, MD, MS
The University of Chicago Medicine
5841 S. Maryland Avenue, MC 5076
Chicago, IL 60637

Clinical Interests

  • Cardiology
  • Interventional cardiology
  • Transradial angiography/intervention
  • Coronary artery disease
  • Peripheral vascular disease
  • Acute coronary syndromes
  • Acute myocardial infarction (heart attacks)
  • Antiplatelet therapies
  • Intravascular ultrasound

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Read More About Dr. Nathan

Dr. Nathan was part of a 17-member team of heart specialists that came together to perform a non-surgical transcatheter aortic-valve implantation (TAVI), giving one woman a new chance at life. Read the story.

Selected Publications

View a partial list of Dr. Sandeep Nathan's publications through the National Library of Medicine's PubMed online database.