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Seon-Kyu Lee, MD, PhD

Associate Professor of Radiology, Surgery and Neurology

Director, Interventional Neuroradiology

Seon-Kyu Lee, MD, PhD, is an expert in interventional and diagnostic neuroradiology. He specializes in neurointerventional procedures (neuroendovascular surgery), including vertebroplasty/kyphoplasty for painful vertebral fractures, intracranial aneurysm, arteriovenous malformation, carotid artery stenting, intracranial stenosis management, tumor embolization, percutaneous sclerotherapy, intractable nose bleeding treatment and other craniofacial neurointerventional procedures. Dr. Lee's goal is to improve quality of care, improve patient safety and facilitate patient education. He devotes special attention to helping patients understand the benefits of preventative screenings and the results of possible treatment options.

Dr. Lee has participated in multiple national and international clinical trials that focus on the neurointerventional managements. He was the principal investigator of the University of Toronto for the CREST (Carotid Revascularization Endarterectomy and Stenting Trial), and the Principal Investigator of Lahey Clinic Medical Center for the IMS-III (Interventional Management of Stroke III), both of them received funding from the National Institute of Health. His research also focuses on stroke prevention and diagnosis.

An accomplished author, Dr. Lee has published more than 50 scientific articles in peer-reviewed journals and has co-written numerous chapters for leading radiology and neurosurgery textbooks. In addition, he frequently delivers presentations on intracranial angioplasty and interventional neuroradiology at national and international conferences.

Practice Location

The University of Chicago Medicine
5841 S. Maryland Avenue
Chicago, IL 60637

Year Started Practice


Board Certification

Diagnostic Radiology

Medical School

Seoul National University

Internship and Residency

Seoul National University, South Korea (Diagnostic Radiology)


The University Health Network (Toronto Western Hospital), ON, Canada (Interventional Neuroradiology)
The Hospital for Sick Children, (University of Toronto), ON, Canada (Interventional Neuroradiology)

Additional Graduate Degrees

MS, Seoul National University, South Korea (radiology)
PhD, Seoul National University, South Korea (radiology)


American Heart Association
American Society of Interventional and Therapeutic Neuroradiology
American Stroke Association
International Society of Magnetic Resonance in Medicine
Korean Medical Association
Korean Radiological Society
Korean Society of Neuroradiology and Head and Neck Radiology
Korean Society of Medical Ultrasound
Korean Society of PACS
Massachusetts Medical Association
Radiological Society of North America
World Federation of Interventional and Therapeutic Neuroradiology

Languages Spoken



Office Phone

(773) 702-3654

Office Fax

(773) 702-1161

Office Postal Address

Seon-Kyu Lee, MD, PhD
The University of Chicago Medicine
5841 S. Maryland Avenue, MC 2026
Chicago, IL 60637

Physician Photo

Clinical Interests

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Learn More About Dr. Lee

Stock car enthusiast, Jim Cox, was sidelined by a nearly blocked brain artery three years after a stroke. Learn how Dr. Lee performed balloon angioplasty and stent placement to open the artery, resuming normal blood flow and allowing Cox to drive his race cars again. Read Jim's story.

Dr. Lee serves as co-medical director of the University of Chicago Medicine's HHT program, which provides multidisciplinary, comprehensive care for patients with hereditary hemorrhagic telangiectasia (HHT).

Grateful for the successful treatment of a dural arteriovenous malformation/fistula (DAVM/DAVF) in his brain, Bill Davis and his wife Judy made a generous donation to support neurovascular surgery research at the University of Chicago Medicine. Read Bill's story.

Soon after Angel Almanza was born, doctors found a hemangioma (benign tumor) on his left arm. When a consult with specialists at Comer Children's Hospital revealed that the "hemangioma" was actually an arteriovenous malformation, Dr. Lee and a team of experts worked quickly and collaboratively to help Angel. Read more.

Selected Publications

View a partial list of Dr. Lee's publications through the National Library of Medicine's PubMed online database.