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Silvana Pannain, MD

Associate Professor of Medicine

Dr. Silvana Pannain is a skilled endocrinologist. She provides advanced endocrinology care for patients who have weight problems or endocrine disorders, such as:

  • Obesity
  • Diabetes
  • Thyroid disease
  • Pituitary disease
  • Adrenal disease
  • Metabolic syndrome (also known as the dysmetabolic syndrome, metabolic syndrome X or insulin resistance syndrome)

She uses highly specialized biochemical testing methods and the newest drug treatments available. Dr. Pannain also serves as director of Chicago Weight, a weight loss program and support group at the University of Chicago. She works closely with teams of specialists--including behavior therapists, dietitians, exercise therapists, bariatric surgeons, cardiologists, lipidologists, hypertension specialists and sleep specialists--to develop comprehensive weight management plans for adult patients. These multidisciplinary teams combine counseling and medical treatment options to help patients lose weight. The Chicago Weight program also teaches patients to maintain a healthy lifestyle by permanently changing diet, exercise and behaviors.

Dr. Pannain's clinical and research interests include obesity, metabolic syndrome and related health conditions, such as obstructive sleep apnea and diabetes. She investigates the metabolic and endocrine aspects of chronic partial sleep loss, which is generally considered a risk factor for obesity and insulin resistance. Additionally, she is studying the effects of gastric bypass surgery on metabolism, sleep and hunger.

Practice Locations

The University of Chicago Medicine
5841 S. Maryland Avenue
Chicago, IL 60637

Duchossois Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637

150 E. Huron Street
Suite 900
Chicago, IL 60611

Year Started Practice


Board Certifications

Internal Medicine
Endocrinology, Diabetes & Metabolism

Medical School

University of Naples

Internship and Residency

University of Naples, Italy
Montefiore Medical Center, Bronx, New York


The University of Chicago Medicine


American Association of Clinical Endocrinologists
North American Association for the Study of Obesity
The Endocrine Society

Languages Spoken



Office Phone

(773) 702-6138

Office Fax

(773) 834-7205

Office Postal Address

Silvana Pannain, MD
The University of Chicago Medicine
5841 S. Maryland Avenue, MC 1027
Chicago, IL 60637

Physician Photo

Clinical Interests

  • Weight management
  • Obesity comorbidities, specifically diabetes and sleep disorders
  • Metabolic syndrome
  • Thyroid disease
  • Pituitary disease
  • Adrenal disease

Request an Appointment

Center for Advanced Medicine
Request an appointment online
or call UCM Connect at

150 E. Huron Street
Request an appointment online
or call (773) 834-4150

Physicians, contact the
Referring Physician Access Line
at 1-877-DOM-2730

Read More About Dr. Pannain

Read about the comprehensive treatment plan Dr. Pannain and a team of medical center physicians developed for Kathleen Colvin, who had congestive heart failure, atrial fibrillation and other conditions--and was at risk for needing kidney dialysis or a transplant.

Selected Publications

View a partial list of Dr. Pannain's publications through the National Library of Medicine's PubMed online database.