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Sonia Kupfer, MD

Assistant Professor of Medicine

Director, Gastrointestinal Cancer Risk and Prevention Clinic

Co-Director, Comprehensive Cancer Risk and Prevention Clinic

Gastroenterologist Sonia Kupfer, MD, is a skilled specialist in all types of digestive system disorders. As a physician in the Comprehensive Cancer Risk and Prevention Clinic and the Celiac Center, she is particularly focused on diagnosing and treating patients with genetic disorders such as hereditary gastrointestinal cancer syndromes and celiac disease.

She has received funding from the National Institutes of Health/National Cancer Institute for studies of genetic associations in African-American colorectal cancer patients. She is an active member of the American Gastroenterological Association and the Collaborative Group of the Americas on Inherited Colorectal Cancer (CGA-ICC), and served as CGA-ICC President in 2016-17.

Practice Locations

The University of Chicago Medicine
5841 S. Maryland Avenue
Chicago, IL 60637

Duchossois Center for Advanced Medicine
5758 S. Maryland Avenue
Chicago, IL 60637

Year Started Practice


Board Certifications

Internal Medicine

Medical School

The University of Chicago Pritzker School of Medicine

Internship, Residency, and Fellowship

The University of Chicago Medicine


American College of Gastroenterology
American Gastroenterology Association

Languages Spoken



Office Phone

(773) 834-8632

Office Fax

(773) 702-2281

Office Postal Address

Sonia Kupfer, MD
The University of Chicago Medicine
KCBD Building
900 E. 57th Street, MB9
Chicago, IL 60637

Physician Photo

Clinical Interests

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Learn More About Dr. Kupfer

Listen to Dr. Kupfer discuss "Cancer and Your Genes" on the WVON Community Health Focus Hour.

In the Center for Clinical Cancer Genetics, Dr. Kupfer provides care for patients who have high colorectal cancer risk or inherited GI cancer syndromes.

Dr. Kupfer was one of seven specialists who cared for a woman battling colorectal cancer during her pregnancy.

Taylor Murphy underwent genetic testing with Dr. Kupfer, which revealed Murphy had Lynch Syndrome and helped direct her course of treatment. Read more.

In a post on our Science Life blog, Dr. Kupfer discusses helping those genetically predisposed to colorectal cancer.

Selected Publications

View a partial list of Dr. Kupfer's publications through the National Library of Medicine's PubMed online database.