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Stefano Guandalini, MD

Professor of Pediatrics

Section Chief, Pediatric Gastroenterology, Hepatology, and Nutrition

Founder and Medical Director, University of Chicago Celiac Disease Center

Stefano Guandalini, MD, is an internationally recognized expert on celiac disease, a digestive disease that damages the small intestine and interferes with absorption of nutrients from food. He is also known for his expertise in the research and treatment of other diarrheal diseases in children.

Dr. Guandalini's clinical and research efforts have greatly influenced the way celiac disease is diagnosed and treated today. His work contributed to the revision of 20-year-old guidelines for celiac disease diagnosis. These guidelines are now used worldwide for the diagnosis of celiac disease in both children and adults.

Dr. Guandalini created the University of Chicago Celiac Disease Center in response to the low rate of celiac disease detection in the United States. This innovative program is dedicated to patient care services, research activities, medical education, and public awareness initiatives in order to increase the rate of celiac diagnoses and improve the lives of celiac patients. The Celiac Disease Center serves patients of all ages.

Dr. Guandalini is the past president of the Federation of International Societies for Pediatric Gastroenterology, Hepatology, and Nutrition. He was selected from a worldwide pool of candidates to be the first president of this federation.

Dr. Guandalini is the president of the North American Society for the Study of Celiac Disease.

He is also a widely recognized expert in probiotics and their effects in children and teenagers.

Dr. Guandalini has been ranked among America’s "Best Doctors" since 2008. In 2012, he received the prestigious title of "Master of Pediatrics" from the Italian Society of Pediatrics.

Practice Locations

The University of Chicago Medicine Comer Children's Hospital
5721 S. Maryland Avenue
Chicago, IL 60637

Child Life Center
19550 Governors Highway
Suite 2500
Flossmoor, IL 60422

Year Started Practice


Medical School

University of Messina


University of Messina, Italy


University of Naples, Italy


American Society for Pediatric Research
European Society for Pediatric Gastroenterology, Hepatology, and Nutrition
Federation of International Societies for Pediatric Gastroenterology, Hepatology, and Nutrition
Italian Society for Pediatric Gastroenterology and Hepatology
North American Society for Pediatric Gastroenterology, Hepatology & Nutrition

Languages Spoken


Office Phone

(773) 702-6418

Office Fax

(773) 702-0666

Office Postal Address

Stefano Guandalini, MD
The University of Chicago Medicine
5841 S. Maryland Avenue, MC 4065
Chicago, IL 60637

Physician Photo

Clinical Interests

  • Celiac disease
  • Chronic diarrhea
  • Recurrent diarrhea
  • Intestinal infections
  • Malabsorption syndromes
  • Food allergies

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Read More About Dr. Guandalini

Our Science Life blog featured a Q&A with Dr. Guandalini about probiotics and prebiotics. Read the post.

Dr. Guandalini talks about caring for children with celiac disease in an advertorial that originally appeared in Chicago Parent.

In 2005, Dr. Guandalini and other renowned celiac disease experts published new guidelines on celiac disease diagnosis.

Watch a video of Dr. Guandalini discussing the Celiac Disease Center and how its unique goals are breaking ground to discover a cure.

Selected Publications

View a partial list of Dr. Guandalini's publications through the National Library of Medicine's PubMed online database.