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Steven J. Chmura, MD, PhD

Associate Professor of Radiation and Cellular Oncology

Dr. Steven Chmura specializes in treating brain, breast, and gastrointestinal cancers. An expert in radiotherapy and stereotactic radiosurgery (SRS), Dr. Chmura uses minimally invasive techniques to minimize tissue damage when diagnosing and treating cancers.

Dr. Chmura is also an expert in using intensity modulated radiation therapy (IMRT) to treat gastrointestinal malignancies such as colon, anal, and pancreatic cancers. Because the radiation is precisely shaped to avoid healthy tissue surrounding the treatment area, this technology allows physicians to target tumors with more powerful doses of radiation.

An active researcher, Dr. Chmura is the principle investigator at the University of Chicago for the Radiation Trials Oncology Group (RTOG). In this role, he is involved in national randomized studies and industry-sponsored studies. His basic science research explores improvements to current radiation approaches. For example, in collaboration with other University of Chicago researchers, Dr. Chmura is working on the development of a BH3 antagonist to increase the therapeutic ratio of radiotherapy. This research earned him the 2005 American Society for Therapeutic Radiology and Oncology (ASTRO) Young Investigator Award. Dr. Chmura is also investigating how to optimize the software used to deliver IMRT to maximize tumor cell killing.

Additionally, he was awarded the 2006 and 2008 American Association of Radiation Oncology Residents teaching Award. Dr. Chmura's teaching responsibilities include lecturing and clinical teaching of medical students and residents.

Practice Location

The University of Chicago Medicine
5841 S. Maryland Avenue
Chicago, IL 60637

Year Started Practice


Medical School

The University of Chicago Pritzker School of Medicine

Internship and Residency

The University of Chicago Medicine


American Society of Therapeutic Radiology and Oncology
Radiation Trials Oncology Group

Language Spoken



Office Phone

(773) 702-4056

Office Fax

(773) 834-7168

Office Postal Address

Steven Chmura, MD, PhD
The University of Chicago Medicine
5841 S. Maryland Avenue, MC 9006
Chicago, IL 60637

Physician Photo

Clinical Interests

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Learn More about Dr. Chmura

Dr. Chmura worked with a multidisciplinary team of specialists to diagnose and treat Leo Galati's primary central nervous system lymphoma (PCNSL), a rare tumor that occurs when cancerous lymphocytes are found in the brain, spinal cord or cerebrospinal fluid. » Read Leo's story.

Bruce Davis is doing well after chemotherapy and targeted radiation shrunk a glioma in his brainstem by more than 60 percent. Dr. Chmura was an important member of the neuroscience team that treated Bruce's tumor. » Read his story.

Selected Publications

View a partial list of Dr. Chmura's publications through the National Library of Medicine's PubMed online database.