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Central Nervous System (CNS) Metastases Clinic

Treatment plans are tailored to each patients’ specific needs.

Managing central nervous system (CNS) metastases requires unique expertise. At the University of Chicago CNS Metastases Clinic, we specialize in the treatment of cancer affecting the body's most complicated organ system.

CNS metastases is cancer that has spread to the brain, spinal cord and cerebrospinal fluid (CSF) from other sites in the body. Our team, comprised of experts in neuro-oncology, neurosurgery and radiation oncology, collaborates closely with colleagues in other cancer specialties to optimize the evaluation and management of patients with CNS metastases.

The CNS Metastases Clinic is home to a comprehensive program focused on the management of:

  • Brain metastases
  • Cerebrospinal fluid metastases, also known as leptomeningeal metastases or carcinomatous meningitis
  • Spinal cord metastases
  • Dural metastases
  • Paraneoplastic syndromes

We offer a multidisciplinary approach to optimized care for CNS metastases. Treatment plans are tailored to each patients’ specific needs and may include:

  • Surgery
  • Radiation, including stereotactic radiosurgery
  • Systemic therapies, including targeted drug therapy, chemotherapy, immunotherapy and hormone therapy
  • Intrathecal (IT) therapies
Browse a list of open CNS clinical trials at the University of Chicago Comprehensive Cancer Center.

In addition to clinical care, which is central to this multidisciplinary program, we are also investigating key issues leading to the development and growth of metastatic tumors. This work is centered in the Ludwig Center for Metastasis Research.