Heart Failure Research

Physicians at the University of Chicago are involved in numerous research studies of promising medications, devices, and diagnostic methods. Because of this, our heart failure patients often gain access to new treatments available through clinical trials--therapies not widely available at other hospitals.

Examples of investigational clinical research under way include the following:

  • Gene therapy studies to improve heart function in people with advanced heart failure
  • The HeartWare left ventricular assist device, a next generation LVAD that increases blood flow and is only the size of a D-cell battery
  • Studies of new drugs to treat acute decompensated heart failure in hospitalized patients
  • A new heart failure pressure measurement system, which continuously monitors heart pressures for better management of heart failure on an outpatient basis
  • Comparison of cardiac imaging methods to determine which tests can best predict which heart failure patients will respond well to cardiac resynchronization therapy

» View a partial list of cardiac clinical trials being conducted at our medical campus

Physician-scientists from the University of Chicago Medicine have taken a special interest in cardiomyopathy research, skeletal muscle regeneration, and other methods to help reverse heart failure on a molecular basis. Other research efforts focus on new ways to improve heart function, preserve organs for transplant, and prevent transplant rejection.